product_name |
Ethylhexyl Methoxycinnamate |
CAS_number |
5466-77-3 |
formula |
C18H26O3 |
molar_mass |
290.40 g/mol |
pub_chem_CID |
5355130 |
drug_bank |
DB13730 |
chem_spider |
4510498 |
bioavailability |
Not well defined |
protein_binding |
Not well defined |
metabolism |
Hepatic |
elimination_halflife |
Not well defined |
FAQ
What is Ethylhexyl Methoxycinnamate (EHMC)?
Ethylhexyl Methoxycinnamate, commonly known as Octyl
Methoxycinnamate or OMC, is an organic compound used primarily in sunscreens and other personal care
products for its UV-filtering capabilities. This ester compound, derived from cinnamic acid, absorbs
UV-B rays, which are primarily responsible for causing sunburn. By incorporating EHMC into sunscreens
and lotions, manufacturers aim to protect the skin from the harmful effects of UV radiation, including
sunburn, photoaging, and potentially even skin cancer. Although it is most commonly known for its use in
sun-blocking products, EHMC is also found in hair care products, lip balms, and even some types of
makeup. The compound is favored due to its relative effectiveness at absorbing UV-B rays and its ease of
formulation into a variety of products. Regulatory bodies like the FDA and the European Commission have
cleared EHMC for use in cosmetic products, though concentrations are often capped to maintain safety and
minimize any potential adverse reactions.
How does Ethylhexyl Methoxycinnamate protect the skin
from UV radiation?
Ethylhexyl Methoxycinnamate functions as a chemical sunscreen by absorbing
UV-B radiation, which ranges from 280 to 320 nanometers in wavelength. When applied to the skin, the
compound absorbs the energy from UV-B rays and dissipates it as heat, thereby preventing the rays from
penetrating deeper layers of the skin. This action effectively reduces the risk of erythema (sunburn),
DNA damage, and other UV-induced ailments. Additionally, EHMC forms a protective barrier that helps
mitigate the impact of free radicals generated by UV radiation, thereby minimizing oxidative stress on
the skin. Its ability to blend seamlessly with other ingredients makes it a versatile component in
broad-spectrum sunscreens, which protect against both UV-A and UV-B radiation. However, while EHMC is
effective in shielding against UV-B rays, it is often combined with other UV filters in formulations to
offer comprehensive protection, as it does not adequately absorb UV-A rays, which also contribute to
skin aging and cancer.
Is Ethylhexyl Methoxycinnamate safe for daily use?
Ethylhexyl
Methoxycinnamate has been widely evaluated for safety by multiple regulatory authorities, including the
U.S. Food and Drug Administration (FDA) and the European Commission. Generally, EHMC is considered safe
for use in cosmetic products at concentrations of up to 7.5% in the U.S. and up to 10% in the European
Union. Numerous studies have conducted toxicology tests, including acute, subchronic, and chronic
exposure assessments, to determine its safety profile. While EHMC is deemed safe for daily application,
it is always prudent for individuals with sensitive skin or known allergies to perform a patch test
before regular use. Some concerns have been raised regarding its potential as an endocrine disruptor;
however, the current consensus in the scientific community suggests that the risk is minimal when EHMC
is used within recommended concentrations. Nonetheless, consumers who are particularly cautious about
exposure to chemical UV filters may opt for products containing physical sunscreens like zinc oxide or
titanium dioxide as alternatives.
Can Ethylhexyl Methoxycinnamate cause skin irritation or
allergic reactions?
While Ethylhexyl Methoxycinnamate is generally considered safe for use, there
have been occasional reports of skin irritation and allergic reactions, particularly in individuals with
sensitive skin. Symptoms can include redness, itching, or rashes, although such reactions are relatively
rare. EHMC can sometimes degrade in sunlight, producing compounds that may cause skin sensitivity. To
minimize the risk of irritation, it is advisable to conduct a patch test before using a product
containing EHMC extensively. Apply a small amount of the product on a discreet area of your skin, such
as the inner arm, and wait for 24-48 hours to see if any adverse reactions occur. Additionally,
combining EHMC with moisturizing agents and antioxidants in formulations can help reduce the risk of
irritation. As with any skincare ingredient, if you experience persistent irritation or any severe
reactions, it is recommended to discontinue use immediately and seek advice from a healthcare
professional.
Are there environmental concerns associated with Ethylhexyl
Methoxycinnamate?
Ethylhexyl Methoxycinnamate has been the subject of scrutiny regarding its
environmental impact, particularly on marine ecosystems. Studies have indicated that EHMC can be harmful
to coral reefs, contributing to coral bleaching even at low concentrations. When sunscreen washes off
during swimming or showering, the compounds can find their way to water bodies and accumulate, posing a
threat to marine life. This has led to some regions, including specific places in Hawaii and Thailand,
banning or considering bans on sunscreens containing EHMC and other similar chemicals. To mitigate these
concerns, consumers are increasingly gravitating towards "reef-safe" sunscreens, which typically exclude
EHMC and other potentially harmful compounds. However, it's important to note that ongoing research is
essential to fully understand the environmental implications of EHMC. Efforts are also being made to
develop new formulations that are effective for UV protection while being less harmful to marine
ecosystems.
Can Ethylhexyl Methoxycinnamate be used during pregnancy?
The use of
Ethylhexyl Methoxycinnamate during pregnancy is generally considered safe by most healthcare
professionals and regulatory bodies, as long as it is used within recommended concentrations. However,
pregnant individuals often seek to minimize exposure to any potentially harmful substances, including
certain chemicals in skincare products. While current evidence does not show significant risks
associated with EHMC usage during pregnancy, some studies have raised questions about its potential as
an endocrine disruptor, although these effects are typically observed at concentrations much higher than
those used in cosmetic products. Given the sensitive nature of pregnancy and the ongoing scientific
investigations into various skincare ingredients, it is advisable to consult with a healthcare provider
before using products containing EHMC or any other chemical UV filters during pregnancy. For those who
prefer to err on the side of caution, mineral-based sunscreens with zinc oxide or titanium dioxide offer
a reliable alternative, providing effective UV protection with a highly regarded safety
profile.
How does Ethylhexyl Methoxycinnamate compare to other UV filters?
Ethylhexyl
Methoxycinnamate is one among many UV filters used in sunscreen formulations, each with its own
strengths and limitations. Compared to physical sunscreens like zinc oxide and titanium dioxide, EHMC
has the advantage of being less visible on the skin, offering a more aesthetic and appealing application
without the white cast that physical sunscreens often leave. However, physical sunscreens generally
provide broader protection against both UV-A and UV-B rays and are less likely to cause skin irritation.
When compared to other chemical UV filters, such as avobenzone and oxybenzone, EHMC stands out for its
effective UV-B absorption but falls short in protecting against UV-A rays unless combined with other
filters. Additionally, some chemical UV filters have been criticized for their potential
endocrine-disrupting effects and environmental concerns, such as coral reef damage. EHMC is often
praised for its stability in formulation and its ability to blend well with other ingredients, making it
a versatile choice for broad-spectrum protection when used in combination with other filters.