Ethylhexyl Methoxycinnamate
product_name Ethylhexyl Methoxycinnamate
CAS_number 5466-77-3
formula C18H26O3
molar_mass 290.40 g/mol
pub_chem_CID 5355130
drug_bank DB13730
chem_spider 4510498
bioavailability Not well defined
protein_binding Not well defined
metabolism Hepatic
elimination_halflife Not well defined


FAQ

What is Ethylhexyl Methoxycinnamate (EHMC)?

Ethylhexyl Methoxycinnamate, commonly known as Octyl Methoxycinnamate or OMC, is an organic compound used primarily in sunscreens and other personal care products for its UV-filtering capabilities. This ester compound, derived from cinnamic acid, absorbs UV-B rays, which are primarily responsible for causing sunburn. By incorporating EHMC into sunscreens and lotions, manufacturers aim to protect the skin from the harmful effects of UV radiation, including sunburn, photoaging, and potentially even skin cancer. Although it is most commonly known for its use in sun-blocking products, EHMC is also found in hair care products, lip balms, and even some types of makeup. The compound is favored due to its relative effectiveness at absorbing UV-B rays and its ease of formulation into a variety of products. Regulatory bodies like the FDA and the European Commission have cleared EHMC for use in cosmetic products, though concentrations are often capped to maintain safety and minimize any potential adverse reactions.

How does Ethylhexyl Methoxycinnamate protect the skin from UV radiation?

Ethylhexyl Methoxycinnamate functions as a chemical sunscreen by absorbing UV-B radiation, which ranges from 280 to 320 nanometers in wavelength. When applied to the skin, the compound absorbs the energy from UV-B rays and dissipates it as heat, thereby preventing the rays from penetrating deeper layers of the skin. This action effectively reduces the risk of erythema (sunburn), DNA damage, and other UV-induced ailments. Additionally, EHMC forms a protective barrier that helps mitigate the impact of free radicals generated by UV radiation, thereby minimizing oxidative stress on the skin. Its ability to blend seamlessly with other ingredients makes it a versatile component in broad-spectrum sunscreens, which protect against both UV-A and UV-B radiation. However, while EHMC is effective in shielding against UV-B rays, it is often combined with other UV filters in formulations to offer comprehensive protection, as it does not adequately absorb UV-A rays, which also contribute to skin aging and cancer.

Is Ethylhexyl Methoxycinnamate safe for daily use?

Ethylhexyl Methoxycinnamate has been widely evaluated for safety by multiple regulatory authorities, including the U.S. Food and Drug Administration (FDA) and the European Commission. Generally, EHMC is considered safe for use in cosmetic products at concentrations of up to 7.5% in the U.S. and up to 10% in the European Union. Numerous studies have conducted toxicology tests, including acute, subchronic, and chronic exposure assessments, to determine its safety profile. While EHMC is deemed safe for daily application, it is always prudent for individuals with sensitive skin or known allergies to perform a patch test before regular use. Some concerns have been raised regarding its potential as an endocrine disruptor; however, the current consensus in the scientific community suggests that the risk is minimal when EHMC is used within recommended concentrations. Nonetheless, consumers who are particularly cautious about exposure to chemical UV filters may opt for products containing physical sunscreens like zinc oxide or titanium dioxide as alternatives.

Can Ethylhexyl Methoxycinnamate cause skin irritation or allergic reactions?

While Ethylhexyl Methoxycinnamate is generally considered safe for use, there have been occasional reports of skin irritation and allergic reactions, particularly in individuals with sensitive skin. Symptoms can include redness, itching, or rashes, although such reactions are relatively rare. EHMC can sometimes degrade in sunlight, producing compounds that may cause skin sensitivity. To minimize the risk of irritation, it is advisable to conduct a patch test before using a product containing EHMC extensively. Apply a small amount of the product on a discreet area of your skin, such as the inner arm, and wait for 24-48 hours to see if any adverse reactions occur. Additionally, combining EHMC with moisturizing agents and antioxidants in formulations can help reduce the risk of irritation. As with any skincare ingredient, if you experience persistent irritation or any severe reactions, it is recommended to discontinue use immediately and seek advice from a healthcare professional.

Are there environmental concerns associated with Ethylhexyl Methoxycinnamate?

Ethylhexyl Methoxycinnamate has been the subject of scrutiny regarding its environmental impact, particularly on marine ecosystems. Studies have indicated that EHMC can be harmful to coral reefs, contributing to coral bleaching even at low concentrations. When sunscreen washes off during swimming or showering, the compounds can find their way to water bodies and accumulate, posing a threat to marine life. This has led to some regions, including specific places in Hawaii and Thailand, banning or considering bans on sunscreens containing EHMC and other similar chemicals. To mitigate these concerns, consumers are increasingly gravitating towards "reef-safe" sunscreens, which typically exclude EHMC and other potentially harmful compounds. However, it's important to note that ongoing research is essential to fully understand the environmental implications of EHMC. Efforts are also being made to develop new formulations that are effective for UV protection while being less harmful to marine ecosystems.

Can Ethylhexyl Methoxycinnamate be used during pregnancy?

The use of Ethylhexyl Methoxycinnamate during pregnancy is generally considered safe by most healthcare professionals and regulatory bodies, as long as it is used within recommended concentrations. However, pregnant individuals often seek to minimize exposure to any potentially harmful substances, including certain chemicals in skincare products. While current evidence does not show significant risks associated with EHMC usage during pregnancy, some studies have raised questions about its potential as an endocrine disruptor, although these effects are typically observed at concentrations much higher than those used in cosmetic products. Given the sensitive nature of pregnancy and the ongoing scientific investigations into various skincare ingredients, it is advisable to consult with a healthcare provider before using products containing EHMC or any other chemical UV filters during pregnancy. For those who prefer to err on the side of caution, mineral-based sunscreens with zinc oxide or titanium dioxide offer a reliable alternative, providing effective UV protection with a highly regarded safety profile.

How does Ethylhexyl Methoxycinnamate compare to other UV filters?

Ethylhexyl Methoxycinnamate is one among many UV filters used in sunscreen formulations, each with its own strengths and limitations. Compared to physical sunscreens like zinc oxide and titanium dioxide, EHMC has the advantage of being less visible on the skin, offering a more aesthetic and appealing application without the white cast that physical sunscreens often leave. However, physical sunscreens generally provide broader protection against both UV-A and UV-B rays and are less likely to cause skin irritation. When compared to other chemical UV filters, such as avobenzone and oxybenzone, EHMC stands out for its effective UV-B absorption but falls short in protecting against UV-A rays unless combined with other filters. Additionally, some chemical UV filters have been criticized for their potential endocrine-disrupting effects and environmental concerns, such as coral reef damage. EHMC is often praised for its stability in formulation and its ability to blend well with other ingredients, making it a versatile choice for broad-spectrum protection when used in combination with other filters.
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